History of Tabex

Introduction: Struggling to quit smoking? Tabex is a popular aid to help smokers quit, and has been available for more than 40 years in post-Soviet states. In this Site, learn about the history of Tabex – from its development to sales in 18 countries around the world – helping you understand how this herbal medicine can be beneficial if you’re trying to break nicotine addiction.

Key Takeaways

  • Tabex has been used as a smoking cessation treatment in Bulgaria for more than 50 years.
  • Tabex contains Cytisine, an alkaloid which binds to nicotine receptors in the brain and produces psychological effects reducing cravings and withdrawal symptoms associated with quitting smoking.
  • Sopharma Pharmaceuticals manufactures Tabex throughout East Europe and it is now available under its original name “Tabex” in 18 countries around the world.
  • Large clinical trials have proven effectiveness of Tabex in helping smokers quit without any lasting side effects when taken correctly under medical supervision

History of Tabex

A scientist examines a test tube with Cytisine in a lab.

Tabex is an original Bulgarian supplement that dates back over 40 years and has been used as a smoking cessation treatment in Bulgaria for more than 40 years. The active ingredient in Tabex, Cytisine, was first identified by scientists in the 19th century.

Since then, extensive research has been conducted into its effects on nicotine addiction. This research contributed to the development of efficient formulas for Tabex and allowed it to be widely accepted as a safe medication used for helping people quit smoking.

In recent decades, usage of Tabex has grown significantly throughout Eastern Europe with nearby countries like Bulgaria mirroring similar increase trends of using this supplement especially developed for quitting smoking attempts.

Nowadays many specialized clinics offer treatments based on cytisine which made it easier to access this effective medication not only within Eastern Europe but also globally both through online sales and subsidizing by governments in certain areas leading to improved health conditions through rising numbers of successful quitting attempts based on tabacco consumption reduction behavior habits changes due to “tabac-free” products like an example set by Tabex existence between treatement options available againts tabacco consuption addictions’ diseases worldwide.

Tabex in Eastern Europe and the Global Market

A woman holding a blister pack of Tabex in various global locations.

Tabex has been licensed as a medication to aid smoking cessation for 40 years in Eastern Europe and is sold under the brand name Tabex since the 1960s. This drug is available in some Eastern European and former Soviet countries, like Russia, and it has become increasingly popular with millions of people using it to quit smoking over five decades.

Sopharma, a Bulgarian pharmaceutical company, has played an integral role distributing Tabex throughout Central and Eastern Europe.

The success of this medicinal product cannot be denied; evidence shows that Tabex was able to help many smokers quit their habit Tipatov reported on 35 cases where patients managed to leave nicotine using just one course (25 tablets)of tabex while reducing withdrawal symptoms significantly.

Its real-world impact not only applies to individuals whose health saw improved quality after quiting but also extends across society through reduced air pollution from cigarettes.

In addition , experts estimated nearly £93 million annual savings thanks to decreased cardiovascular hospital admissions resulting from these same benefits. Regardless of the economic benefits , its principal value remains in giving relief from smoking dependence at negligible risk or lasting side effects when taken correctly.

By familiarizing itself with relevant market dynamics such as availability , marketing profile , licensing -associated factors among other things ; tabex successfully made itself into both a regional giant within eastern europe as well as showing staying power globally.

Complex problems may take complex solutions but often times going back to basics can make all the difference when addressing simple issues like tobacco addiction. It is clear why tabex continues being prescribed despite arriving on market several decades ago : efficacy paired with safety makes a winning combination no matter which region we look into.

Who invented Tabex?

Tabex was invented by Bulgarian scientists in the 1960s. According to the history the key people involved in developing Tabex were:

  • Prof. Isaev who isolated cytisine from the golden chain plant in 1962 and started research on creating the Tabex supplement.
  • Daleva and Sheykova who conducted pharmacological studies on cytisine in 1963.
  • The technology for manufacturing Tabex was developed between 1962 and 1964.
  • The first batch of Tabex was manufactured in September 1964.

So Professor Isaev is widely credited as the inventor of Tabex, along with his colleagues who helped conduct research and develop the manufacturing process. Tabex is based on cytisine, an alkaloid found in plants that acts similar to nicotine. Bulgarian scientists discovered the potential of cytisine as a respiratory stimulant in the 1950s and 1960s.

However, the history of cytisine itself dates back much further. The alkaloid cytisine was first isolated and chemically analyzed in 1865 by A. Orehov. Pharmacological studies of cytisine began in the early 20th century.

So in summary, while Professor Isaev and his colleagues are credited with inventing the Tabex supplement in the 1960s, their work built on earlier research into the active ingredient – cytisine – conducted by scientists dating back over a century.


Tabex is a smoking cessation aid developed and manufactured by Sopharma Pharmaceuticals in Eastern Europe Bulgaria. It has been used for more than 40 years with proven efficacy in helping smokers quit.

Its active ingredient, cytisine, is an alkaloid which binds to the nicotine receptors in the brain and produces psychological effects that help reduce cravings and withdrawal symptoms associated with quitting smoking.

The technology for Tabex manufacture was developed between 1962-1964 and since then it has become increasingly popular among customers of Eastern Europe countries like Bulgaria, Poland, Ukraine, Romania and Russia as a safe means to beat nicotine addiction.

Large clinical trials have demonstrated its safety profile and established its effectiveness as a smoking cessation tool. Today it is available under the name “Tabex” in 18 different countries around the world providing an alternative to other pharmacotherapy or nicotine replacement therapies offered on the global market today.


1. What is Tabex?

Tabex is a brand of smoking cessation medication developed by the German pharmaceutical company Boehringer Ingelheim in 1969.

2. How does Tabex work?

Tabex works by reducing the craving for nicotine, and blocking its effects on the body when consumed. It also helps to reduce withdrawal symptoms experienced when quitting smoking.